Most projects involving sound design and audio tracks will include dedicated audio files. TouchDesigner is capable of reading and playing many standard audio formats such as MP3, AIFF, and WAV, through the use of the Audio File In CHOP and the Audio Play CHOP. These files can be looped, cued, re-pitched, and trimmed, allowing for flexible uses of samples and audio files.
There are many different external audio interfaces that can be used with TouchDesigner. It is best to refer to the Derivative TouchDesigner Wiki and Forum for a more comprehensive list of compatible devices.
There are two different audio drivers that can be accessed from within TouchDesigner. DirectSound has been available since previous versions of TouchDesigner, and has been developed as a part of DirectX. It is a mature driver, having been in development for many years, and provides relatively low latencies even under heavy use.
Once inputs and outputs are setup in TouchDesigner, they can be routed much like any other data.